We present a study on the usability of three different user interfaces for an augmented reality glasses system. The application is intended for use in hospitals by nursing professionals. During wound care, images can be taken with the Microsoft HoloLens 2 and measured directly. The photos must always be taken at the same distance from the wound to follow the healing process. We present and juxtapose three aim assistants to take a picture of the wound and acquire wound data. To gain a first impression about the goodness of usability and the preferred targeting assistant, we conducted a small usability study. Participants were asked to perform wound measuring tasks using our application’s varying user interfaces. In this study, we identified strengths and weaknesses for each user interface based on the conducted research and identified approaches for further improvements.