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Detection of air trapping in chronic obstructive pulmonary disease by low frequency ultrasound
(2012)
Background: Spirometry is regarded as the gold standard for the diagnosis of COPD, yet the condition is widely underdiagnosed. Therefore, additional screening methods that are easy to perform and to interpret are needed. Recently, we demonstrated that low frequency ultrasound (LFU) may be helpful for monitoring lung diseases. The objective of this study was to evaluate whether LFU can be used to detect air trapping in COPD. In addition, we evaluated the ability of LFU to detect the effects of short-acting bronchodilator medication.Methods: Seventeen patients with COPD and 9 healthy subjects were examined by body plethysmography and LFU. Ultrasound frequencies ranging from 1 to 40 kHz were transmitted to the sternum and received at the back during inspiration and expiration. The high pass frequency was determined from the inspiratory and the expiratory signals and their difference termed F. Measurements were repeated after inhalation of salbutamol.Results: We found signi ficant differences in F between COPD subjects and healthy subjects. These differences were already significant at GOLD stage 1 and increased with the severity of COPD. Sensitivity for detection of GOLD stage 1 was 83% and for GOLD stages worse than 1 it was 91%. Bronchodilator effects could not be detected reliably.Conclusions: We conclude that low frequency ultrasound is cost-effective, easy to perform and suitable for detecting air trapping. It might be useful in screening for COPD
Electro-magnetic acoustic transducers (EMATs) are intended as non-contact and non-destructive ultrasound transducers for metallic material. The transmitted intensities from EMATS are modest, particularly at notable lift off distances. Some time ago a concept for a “coil only EMAT” was presented, without static magnetic field. In this contribution, such compact “coil only EMATs” with effective areas of 1–5 cm2 were driven to excessive power levels at MHz frequencies, using pulsed power technologies. RF induction currents of 10 kA and tens of Megawatts are applied. With increasing power the electroacoustic conversion efficiency also increases. The total effect is of second order or quadratic, therefore non-linear and progressive, and yields strong ultrasound signals up to kW/cm2 at MHz frequencies in the metal. Even at considerable lift off distances (cm) the ultrasound can be readily detected. Test materials are aluminum, ferromagnetic steel and stainless steel (non-ferromagnetic). Thereby, most metal types are represented. The technique is compared experimentally with other non-contact methods: laser pulse induced ultrasound and spark induced ultrasound, both damaging to the test object’s surface. At small lift off distances, the intensity from this EMAT concept clearly outperforms the laser pulses or heavy spark impacts.
Efficient photoluminescence (PL) spectra from GaN and InGaN layers at temperatures up to 1100 K are observed with low noise floor and high dynamic resolution. A number of detailed spectral features in the PL can be directly linked to physical properties of the epitaxial grown layer. The method is suggested as an in situ monitoring tool during epitaxy of nitride LED and laser structures. Layer properties like thickness, band gap or film temperature distribution are feasible.
In this work we report the first quasi-continuous in-situ photoluminescence study of growing InGaN LED structures inside an industrial-grade metal-organic vapor phase epitaxy (MOVPE) reactor at growth temperature. The photoluminescence spectra contain information about temperature, thickness and composition of the epitaxial layers. Furthermore, the in-situ spectra – even at an early stage of the growth of the active region – can be used to predict the photoluminescence emission wavelength of the structure at room temperature. In this study an accuracy of this predicted wavelength in the range of ± 1.3 nm (2σ) is demonstrated. This technique thus appears suitable for closed-loop control of the emission wavelength of InGaN LEDs already during growth.
A simple copper coil without a voluminous stationary magnet can be utilized as a non-contacting transmitter and as a detector for ultrasonic vibrations in metals. Advantages of such compact EMATs without (electro-)magnet might be: applications in critical environments (hot, narrow, presence of iron filings…), potentially superior fields (then improved ultrasound transmission and more sensitive ultrasound detection).
The induction field of an EMAT strongly influences ultrasound transduction in the nearby metal. Herein, a simplified analytical method for field description at high liftoff is presented. Within certain limitations this method reasonably describes magnetic fields (and resulting eddy currents, inductances, Lorentz forces, acoustic pressures) of even complex coil arrangements. The methods can be adapted to conventional EMATS with a separate stationary magnet.
Increased distances (liftoff) are challenging and technically relevant, and this practical question is addressed: with limited electrical power and given free space between transducer and target metal, what would be the most efficient geometry of a circular coil? Furthermore, more complex coil geometries (“butterfly coil”) with a concentrated field and relatively higher reach are briefly investigated.
Background:
Detection of influential actors in social media such as Twitter or Facebook plays an important role for improving the quality and efficiency of work and services in many fields such as education and marketing.
Methods:
The work described here aims to introduce a new approach that characterizes the influence of actors by the strength of attracting new active members into a networked community. We present a model of influence of an actor that is based on the attractiveness of the actor in terms of the number of other new actors with which he or she has established relations over time.
Results:
We have used this concept and measure of influence to determine optimal seeds in a simulation of influence maximization using two empirically collected social networks for the underlying graphs.
Conclusions:
Our empirical results on the datasets demonstrate that our measure stands out as a useful measure to define the attractors comparing to the other influence measures.
A Large and Quick Induction Field Scanner for Examining the Interior of Extended Objects or Humans
(2017)
This study describes the techniques and signal properties of a large, powerful, and linear-scanning 1.5 MHz induction field scanner. The mechanical system is capable of quickly reading the volume of relative large objects, e.g., a test person. The general approach mirrors Magnetic Induction Tomography (MIT), but the details differ considerably from currently-described MIT systems: the setup is asymmetrical, and it operates in gradiometric modalities, either with coaxial excitation with destructive interference or with a single excitation loop and tilted receivers. Following this approach, the primary signals were almost completely nulled, and test objects' real or imaginary imprint was obtained directly. The coaxial gradiometer appeared advantageous: exposure to strong fields was reduced due to destructive interference. Meanwhile, the signals included enhanced components at higher spatial frequencies, thereby obtaining a gradually improved capability for localization. For robust signals, the excitation field can be powered towards the rated limits of human exposure to time-varying magnetic fields. Repeated measurements assessed the important signal integrity, which is affected by the scanner´s imperfections, particularly any motions or respiratory changes in living beings during or between repeated scans. The currently achieved and overall figure of merit for artifacts was 58 dB for inanimate test objects and 44 dB for a test person. Both numbers should be understood as worst case levels: a repeated scan with intermediate breathing and drift/dislocations requires 50 seconds, whereas a single measurement (with respiratory arrest) takes only about 5 seconds.
This experimental study demonstrates for the first time a solid-state circuitry and design for a simple compact copper coil (without an additional bulky permanent magnet or bulky electromagnet) as a contactless electromagnetic acoustic transducer (EMAT) for pulse echo operation at MHz frequencies. A pulsed ultrasound emission into a metallic test object is electromagnetically excited by
an intense MHz burst at up to 500 A through the 0.15 mm filaments of the transducer. Immediately thereafter, a smoother and quasi “DC-like” current of 100 A is applied for about 1 ms and allows an
echo detection. The ultrasonic pulse echo operation for a simple, compact, non-contacting copper coil is new. Application scenarios for compact transducer techniques include very narrow and
hostile environments, in which, e.g., quickly moving metal parts must be tested with only one, non-contacting ultrasound shot. The small transducer coil can be operated remotely with a cable
connection, separate from the much bulkier supply circuitry. Several options for more technical and fundamental progress are discussed.
Photoluminescence (PL) in GaN or InGaN layers monitored during epitaxial growth at high temperatures permits a quasi-continuous in situ characterization of opto-electronic properties. Therefore, epitaxial parameters can now be optimized at the earliest possible stage. A pulsed and high-power UV laser was required for PL excitation at high temperatures. Herein, the underlying nonlinear mechanism was studied via time-resolved PL experiments and rate equation-based modeling. A temperature-activated and saturable path for quenching over defects was identified. Beyond the saturation threshold, reasonably-intensive PL sets in. At high temperatures not only is the near band gap-PL present, but also—as a new observation—a defect-assisted PL emerges. Apart from these specific electronic transitions in high-temperature PL of GaN, a simple, but reasonably predictive model of the luminescent thin film has been set up to track down interference fringes in the PL spectra. It is worth mentioning that the spectral PL modulation (aiming at the Purcell effect) is often mixed up with ordinary Fabry–Pérot interference. A distinction has become key to properly analyze the spectral signatures of high-temperature PL in order to provide a reliable in situ characterization of GaN layers during epitaxial growth
Background:
Influential actors detection in social media such as twitter or Facebook can play a major role in gathering opinions on particular topics, improving the market
-
ing efficiency, predicting the trends, etc.
Proposed methods:
This work aims to extend our formally defined
T
measure to
present a new measure aiming to recognize the actor’s influence by the strength of
attracting new important actors into a networked community. Therefore, we propose a
model of the actor’s influence based on the attractiveness of the actor in relation to the
number of other attractors with whom he/she has established connections over time.
Results and conclusions:
Using an empirically collected social network for the
underlying graph, we have applied the above-mentioned measure of influence in
order to determine optimal seeds in a simulation of influence maximization. We study
our extended measure in the context of information diffusion because this measure is
based on a model of actors who attract others to be active members in a community.
This corresponds to the idea of the IC simulation model which is used to identify the
most important spreaders in a set of actors.
Keywords: Actor influence, Social media networks, Twitter, IC model, Information
diffusion, Independent cascade model, T measure
So far, researchers have used a wellbeing-centered approach to catalyze successful intergenerational collaboration (IGC) in innovative activities. However, due to the subject’s multidisciplinary nature, there is still a dearth of comprehensive research devoted to constructing the IGC system. Thus, the purpose of this study is to fill a research void by providing a conceptual framework for information technology (IT) system designers to use as a jumping-off point for designing an IGC system with a wellbeing-oriented design. A systematic literature study was conducted to identify relevant terms and develop a conceptual framework based on a review of 75 selected scientific papers. The result consists of prominent thematic linkages and a conceptual framework related to design technology for IGC systems. The conceptual framework provides a comprehensive overview of IGC systems in the innovation process by identifying five barrier dimensions and using six wellbeing determinants as IGC catalysts. Moreover, this study discusses future directions for research on IGC systems. This study offers a novel contribution by shifting the technology design process from an age-based design approach to wellbeing-driven IGC systems. Additional avenues for investigation were revealed through the analysis of the study’s findings.
In this study, we looked at the competencies and changes in the competency spectrum required for global start-ups in the digital age. Specifically, we explored intergenerational collaboration as an intervention in which experienced business-people from senior adult groups support young entrepreneurs. We conducted a Delphi study with 20 experts from different disciplines, considering the study context. The results of this study shed light on understanding the necessary competencies of entrepreneurs for intergenerationally supported start-up innovation by providing 27 competencies categorized as follows: intergenerational safety facilitation, cultural awareness, virtues for growth, effectual creativity, technical expertise, responsive teamwork, values-based organization, and sustainable network development. In addition, the study results also reveal the competency priorities and the minimum requirements for each competency group based on the global innovation process and can be used to develop a readiness assessment for start-up entrepreneurs.